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  1. Estrogen, specifically estradiol, can cause side effects in dogs123. These include:
    • Excessive drinking
    • Excessive urination
    • Lethargy
    • Alopecia
    • Clitoral hypertrophy
    • Vaginitis (especially in prepubertal bitches)
    • Increased activity of skin sebaceous glands
    • Mild epiphora
    • Alterations in hepatic function
    • Feminization in males
    • Toxicity to bone marrow in small animals, which may lead to blood dyscrasias
    If your dog experiences unusual bruising or bleeding, or any other abnormalities, stop giving them the medication and call your veterinarian1.
    Learn more:
    Other side effects of estrogen, specifically estradiol, include: Excessive drinking Excessive urination Lethargy Alopecia If your dog experiences unusual bruising or bleeding, or any other abnormalities, stop giving them the medication and call your veterinarian.
    www.cuteness.com/article/estrogen-side-effects-dogs
    Common adverse effects are clitoral hypertrophy, vaginitis (especially in prepubertal bitches), increased activity of skin sebaceous glands, mild epiphora, and alterations in hepatic function.
    www.merckvetmanual.com/management-and-nutrit…
    In males, estradiol can cause feminization. Estrogens are considered toxic to bone marrow in small animals and may lead to blood dyscrasias. Overdose of estrogen has been reported to cause anemia and thrombocytopenia.
    www.petplace.com/article/drug-library/drug-library/li…
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  3. 12 Potential Dog Estrogen Side Effects - Small Animal …

    Giving estrogen to dogs can have several side effects, these may include weight gain, loss of appetite, changes in behavior, fever, vaginal bleeding, exercise intolerance, and an increased risk of certain health conditions such as …

  4. Incurin® (estriol) - PetMD

    Jul 6, 2022 · However, high doses can cause unwanted side effects and illness. Incurin ® is a low dose, short-acting estrogen that is generally regarded as safe for use in female dogs with estrogen-responsive urinary incontinence.

  5. Incurin for Dogs: Side Effects and Dosages - GoodRx

    Jun 6, 2024 · When given at the appropriate dosage, there are no serious side effects associated with Incurin for dogs. In part, this is because estriol is a short-acting estrogen. This makes it safer to give to dogs than other types of …

  6. Diethylstilbestrol (DES) 101: What You Need to Know if Your Pet is ...

  7. 5 Dog Incontinence Medications That Could Help

    Feb 12, 2024 · The most common side effects include gastrointestinal issues like vomiting or estrogen-related changes like a swollen vulva. Estrogens carry the risk of bone marrow toxicity, but this is uncommon when following your …

  8. INCURIN® TABLETS - Merck Animal Health USA

    Incurin is indicated for the control of estrogen-responsive urinary incontinence in ovariohysterectomized dogs. The most common side effects associated with Incurin treatment under field conditions included loss of appetite, vomiting, …

  9. Estriol | VCA Animal Hospitals

  10. Hormonal Control of Estrus in Dogs - Merck Veterinary Manual

  11. Pharmacotherapeutics in Urinary Incontinence in Dogs and Cats