Diethylstilbestrol is also known as DES. It is a synthetic estrogen that is commonly used to treat urinary incontinence in spayed female dogs. It is not available from a veterinary pharmaceutical manufacturer, only through a specialty compounding pharmacy, though veterinarians can prescribe it for off-label use.

Diethylstilbestrol (DES) is a hormone classified as a synthetic, nonsteroidal estrogen. It is used primarily for treatment of urinary incontinence in spayed female dogs. It is thought that DES increases the responsiveness of the smooth muscle of the bladder neck to nerve activity, tightening the muscle and preventing leakage of urine.

Diethylstilbestrol, commonly abbreviated DES, is a medication used to treat estrogen responsive urinary incontinence (wetting themselves or inability to hold urine) in spayed female dogs. It is also used to treat benign prostatic hypertrophy, BPH, which is an enlarged prostate in male dogs.

Diethylstilbestrol is a synthetic estrogen hormone used in the treatment of urinary incontinence in female dogs and cats, benign prostatic hypertrophy (prostate enlargement) in male dogs and the prevention of pregnancy after mismating in dogs and cats.