Although widely associated with various inflammatory diseases, mast cells have an evolutionarily conserved role in host defence and have been shown to make functional contributions to immunity to ...

As anaphylatoxins, C3a and C5a trigger the mast cell and basophilic release of mediators ... per se and by C5a with the consequent secretion of mediators of the acute inflammatory response ...

Tuberculosis (TB), caused by the bacterium Mycobacterium tuberculosis ( Mtb ), infects approximately one-fourth of the world’s population. While most infected individuals are asymptomatic, latent TB ...

Upon binding with SCFA, a chemical cascade ensues, culminating with the synthesis and secretion of prostaglandins ... "The activation of mast cell is a common cause of various allergic diseases and ...

Research in our lab is focussed on identifying the signalling pathways and molecules controlling secretion from neurones and mast cells, with a special interest in voltage-gated (CaV), ligand-gated ...

Garg K, Ryan JJ, Bowlin GL (2011), Modulation of Mast Cell Adhesion, Proliferation and Cytokine Secretion on Electrospun Bioresorbable Vascular Grafts, Journal of Biomedical Materials Research: Part A ...

A multi-institutional group of researchers led by the Hubrecht Institute and Roche's Institute of Human Biology has developed ...

The red module may be beneficial in aging via the preferential degranulation of mast cells; release of glucosamines ... significantly higher procollagen secretion vs. control in human ...

38 “The absence of neutrophils in chronic tendinopathies has led researchers and clinicians to question the inflammatory basis of so called tendinitis” The best characterised, early function of mast ...

Key observed abnormalities in diabetic patients include reduced muscle mass and strength, abnormal lipid deposition, fiber atrophy, and altered myokine secretion ... cell populations (MuSCs, ...

Rep. Brian Mast (R-Fla.) said former Vice President Mike Pence’s life “wasn’t really in peril” when former President Trump allegedly said “So what?” on Jan. 6, 2021, in response to an ...