Kupffer cell–like clusters (right) assume the function of Kupffer cells (left). These are aggregations of multiple cells that form net-like filters with high capacity in the collateral vessels ...

More information: Kupffer cells dictate hepatic responses to the ... Cholesterol is a type of fat that is essential for many ...

Discover which hepatocytes are suitable for various study types and learn why hepatocytes are critical for ADME/DMPK ...

This new article publication from Acta Pharmaceutica Sinica B, discusses how heme oxygenase 1-mediated ferroptosis in Kupffer ...

Giant Cells Step in to Compensate for Impaired Immune Function Sep. 28, 2023 — A team of researchers has uncovered a previously unknown compensatory mechanism found in liver disease. If Kupffer ...

As noted above, stellate cell activation is the central event in hepatic fibrosis. Activation consists of 2 major phases: (1) initiation (also called apreinflammatory stage) and (2) perpetuation ...

Cells manage a wide range of functions in their tiny package — growing, moving, housekeeping, and so on — and most of those functions require energy. But how do cells get this energy in the ...

Using miniature human intestines grown in the lab, tuft cells have been found to act as regenerative stem cells in the human ...

Northwestern Medicine scientists have discovered a new mechanism that controls a specialized group of T-cells, known as ...

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Intestinal tuft cells divide to make new cells when immunological cues trigger them. Additionally, in contrast to progenitor- ...

A research group is the first in the world to succeed in constructing artificial cell nuclei by injecting purified DNA ...