Reno is a city in the northwest section of the U.S. state of Nevada, along the Nevada–California border. It is the county seat and most populou…Reno is a city in the northwest section of the U.S. state of Nevada, along the Nevada–California border. It is the county seat and most populous city of Washoe County. Sitting in the High Eastern Sierra foothills, in the Truckee River valley, on the eastern side of the Sierra Nevada, it is about 23 miles northeast of Lake Tahoe. Known as "The Biggest Little City in the World", it is the 80th most populous city in the United States, the 3rd most populous city in Nevada, and the most populous in Nevada outside the Las Vegas Valley. The city had a population of 264,165 at the 2020 census.