Differentiating lower motor neuron syndromes | Journal of …
WEBLower motor neuron (LMN) syndromes typically present with muscle wasting and weakness and may arise from pathology affecting the distal motor nerve up to the level of the anterior horn cell. A variety of hereditary causes are recognised, including spinal muscular atrophy, distal hereditary motor neuropathy and LMN variants of familial motor neuron disease. Recent genetic advances have resulted ...
Chronic inflammatory demyelinating polyneuropathy: update on …
WEBChronic inflammatory demyelinating polyneuropathy (CIDP) is an immune-mediated neuropathy typically characterised by symmetrical involvement, and proximal as well as distal muscle weakness (typical CIDP). However, there are several ‘atypical’ subtypes, such as multifocal acquired demyelinating sensory and motor neuropathy (Lewis-Sumner syndrome) and ‘distal acquired demyelinating ...
Multidisciplinary consensus guideline for the diagnosis and …
WEBBackground We aimed to create a multidisciplinary consensus clinical guideline for best practice in the diagnosis, investigation and management of spontaneous intracranial hypotension (SIH) due to cerebrospinal fluid leak based on current evidence and consensus from a multidisciplinary specialist interest group (SIG). Methods A 29-member SIG was established, with members from neurology ...
Homepage | Journal of Neurology, Neurosurgery and Psychiatry …
WEB3 days ago — Journal of Neurology, Neurosurgery and Psychiatry is a Plan S compliant Transformative Journal. Journal of Neurology, Neurosurgery and Psychiatry (JNNP)'s ambition is to publish the most ground-breaking and cutting-edge research from around the world. Encompassing the entire genre of neurological sciences, our focus is on the common disorders (stroke, multiple sclerosis, Parkinson's disease ...
The basics of electromyography | Journal of Neurology, …
WEBElectromyography (EMG), the recording of electrical activity in muscle, should be regarded as an extension of the clinical examination. It can distinguish myopathic from neurogenic muscle wasting and weakness. It can detect abnormalities such as chronic denervation or fasciculations in clinically normal muscle. It can, by determining the distribution of neurogenic abnormalities, differentiate ...
Practical approach to the diagnosis of adult-onset …
WEBAdult-onset leukodystrophies and genetic leukoencephalopathies comprise a diverse group of neurodegenerative disorders of white matter with a wide age of onset and phenotypic spectrum. Patients with white matter abnormalities detected on MRI often present a diagnostic challenge to both general and specialist neurologists. Patients typically present with a progressive syndrome including various ...
EEG in neurological conditions other than epilepsy: when does it …
WEBAlthough the electroencephalogram (EEG) is a reliable test to assess cerebral function, its value in diagnosis and evaluation of neurological conditions apart from epilepsy has been largely superceded in recent years by other investigations with greater specificity and sensitivity. Is EEG still worthwhile, and in which cases can it provide information that affects management? Broadly speaking ...
The vegetative state - Journal of Neurology, Neurosurgery
WEBThe definition, diagnosis, prognosis and pathology of this state are discussed, together with the legal implications In the 30 years since this state was first described and named1 it has provoked intense debate not only among clinical scientists and health professionals but also among moral philosophers and lawyers. Considering its relative rarity there is also, courtesy of the media, an ...
What is brain fog? - Journal of Neurology, Neurosurgery
WEBOthers have suggested that brain fog is a ‘constellation of cognitive symptoms’, which may be due to ‘inflammatory molecules’ and ‘focal brain inflammation’. 5 Yet, we rarely hear reports of brain fog from patients with acute neuroinflammatory conditions or neurodegenerative dementia. And while we might describe a clouding of ...
Idiopathic intracranial hypertension: consensus guidelines on ...
WEBThe aim was to capture interdisciplinary expertise from a large group of clinicians, reflecting practice from across the UK and further, to inform subsequent development of a national consensus guidance for optimal management of idiopathic intracranial hypertension (IIH). Methods Between September 2015 and October 2017, a specialist interest group including neurology, neurosurgery ...